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Science / Company profile

Bioptimus

What Bioptimus does

Bioptimus is a private, France-incorporated AI-for-biology company building foundation models intended to connect biological data across multiple scales (e.g., molecular → cellular → tissue → organism/patient). Publicly, the company positions its work as a “world model for biology,” with H-Optimus focused on pathology and M-Optimus positioned as a multi-modality, multi-scale successor. In addition to model development, Bioptimus emphasizes building data infrastructure—most prominently STELA (Spatial Tissue Embedding Learning Atlas)—to generate harmonized, clinically linked spatial and multi-omics data intended to power the next generation of its foundation models.

Bioptimus’s business model appears to blend (1) shipping deployable model offerings for pathology workflows (including marketplace distribution for H-Optimus variants) with (2) offering early access/partner programs for the broader M-Optimus “world model” and its associated data engine (STELA). The company also highlights selective integrations with major platform providers for compute and deployment (e.g., NVIDIA compute access; AWS Marketplace / SageMaker access), targeting enterprise and research users such as healthcare and life-sciences organizations and research institutions.

Strategically, Bioptimus has moved from seed-stage stealth/out-of-stealth in early 2024 to releasing an open-source pathology foundation model in July 2024, then iterating on deployable pathology models through 2025 while preparing the multi-modality “world model” (M-Optimus) and a large-scale clinically linked spatial data initiative (STELA) launched in March 2026. Recent partnerships in 2026 (including Cancer Research Horizons and FFCD) indicate an expanding footprint for clinically linked cohorts intended to scale STELA’s data foundation.

News

Company record

Aug 20, 2026 · Official · BioptimusBioptimus partners with Cancer Research Horizons to advance AI-powered precision medicine

Bioptimus announced a partnership with Cancer Research Horizons (Cancer Research UK’s innovation engine), describing access to S:CORT (a colorectal cancer dataset) intended to train and evaluate its AI foundation model and to add a UK patient cohort to STELA.

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Jun 30, 2026 · Official · BioptimusPartnership with French cancer research network FFCD expands Bioptimus’s STELA programme

Bioptimus announced a partnership with FFCD, stating it grants access to clinical trial data covering more than 3,000 GI cancer patients and accelerates STELA’s goal of building a large global AI biology model.

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Mar 25, 2026 · Official · BioptimusBioptimus Announces STELA: The World’s Largest Clinically Linked Spatial Biology Atlas, alongside key partners 10x Genomics and Broad Clinical Labs

Bioptimus announced the launch of STELA, describing goals to profile up to 100,000 patient specimens and partnerships with 10x Genomics (Xenium spatial transcriptomics) and Broad Clinical Labs to generate harmonized multi-omics and clinically linked spatial data to scale M-Optimus.

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Dec 17, 2025 · Official · BioptimusBioptimus Unveils M-Optimus, a World Model for Biology

Bioptimus announced unveiling M-Optimus, describing it as its inaugural world model for biology designed to combine multiple biological modalities and simulate biology at scale, with an early access program for pioneer clients.

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Sep 11, 2025 · Official · BioptimusBioptimus Assembles Elite Scientific Advisory Board to Build Next-Gen AI Models for Biology

Bioptimus announced the formation of a Scientific Advisory Board (SAB) to guide its scientific strategy for building large-scale AI models across life sciences.

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Aug 07, 2025 · Official · BioptimusBioptimus Strengthens Commercial and Scientific Leadership with Key Hires

Bioptimus announced key leadership hires: Ketan Patel (Head of Product) and Tokuwa Kanno (Head of Computational Biology), following the appointment of a Chief Commercial Officer.

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Jul 10, 2025 · Official · BioptimusBioptimus Appoints Julie Gerardi as Chief Commercial Officer

Bioptimus announced the appointment of Julie Gerardi as Chief Commercial Officer, describing experience in biotech commercialization and pharma partnerships.

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Jun 11, 2025 · Official · BioptimusBioptimus Secures Access to NVIDIA Compute Resources to its Accelerate Foundation Model for Biology

Bioptimus announced access to NVIDIA DGX Cloud Lepton compute resources, citing a collaboration involving Sofinnova Partners and GPU capacity credits from NVIDIA to accelerate foundation model training.

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Show 4 earlier updates
May 06, 2025 · Official · BioptimusBioptimus Launches H-Optimus-1 on AWS Marketplace, Bringing Powerful AI to Pathology Workflows Worldwide

Bioptimus announced H-Optimus-1 availability on AWS Marketplace, describing best-in-class performance across pathology tasks and deployment in secure AWS environments.

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Jan 14, 2025 · Official · BioptimusBioptimus hits $76M funding milestone and prepares to launch groundbreaking foundation model for biology

Bioptimus announced a $76M funding milestone, including a $41M cash injection led by Cathay Innovation, and discussed the company’s plans to release a new multi-scale, multi-modal foundation model in 2025.

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Jul 11, 2024 · Official · BioptimusBioptimus launches H-Optimus-0, the world’s largest open-source AI foundation model for pathology

Bioptimus announced H-Optimus-0 release as an open-source pathology foundation model trained on a dataset derived from histopathology slides across clinical practices; the company highlighted 1.1B parameters and performance across diagnostic tasks.

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Feb 20, 2024 · Official · BioptimusEx-Google DeepMind and Owkin scientists team up to create Bioptimus to build the first universal AI foundation model for biology

Bioptimus announced its emergence from stealth and a $35M seed round led by Sofinnova Partners, alongside Bpifrance Large Venture and additional investors, describing a universal foundation model approach across biological scales.

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Source map · 2 recurring channels · 39 references
BioptimusOfficial Site · monitor↗MTS Frontier / Control RoomCurated Feed · monitor↗Official company sourceOfficial Reference · reference↗app.dealroom.coReporting · reference↗arxiv.orgReporting · reference↗bioct.orgReporting · reference↗biophytis.comReporting · reference↗bioutah.orgReporting · reference↗caplight.comReporting · reference↗cathaycapital.comReporting · reference↗cbinsights.comReporting · reference↗crunchbase.comReporting · reference↗d3bql97l1ytoxn.cloudfront.netReporting · reference↗d5bp8bijhhba2.cloudfront.netReporting · reference↗datocms-assets.comReporting · reference↗dealroom.coReporting · reference↗edrn.cancer.govReporting · reference↗en.media.businessfrance.frReporting · reference↗en.wikipedia.orgReporting · reference↗event.businessfrance.frReporting · reference↗fortressbiotech.comReporting · reference↗google.comReporting · reference↗hsbcinnovationbanking.comReporting · reference↗job-boards.greenhouse.ioReporting · reference↗lemonde.frReporting · reference↗linkedin.comReporting · reference↗mobicheckin-assets.s3.eu-west-1.amazonaws.comReporting · reference↗pages.awscloud.comReporting · reference↗pappers.frReporting · reference↗pitchbook.brightspotcdn.comReporting · reference↗portalcris.vdu.ltReporting · reference↗reddit.comReporting · reference↗sbi2.orgReporting · reference↗seedtable.comReporting · reference↗support.greenhouse.ioReporting · reference↗table.mediaReporting · reference↗techcrunch.comReporting · reference↗uk.linkedin.comReporting · reference↗user-assets-unbounce-com.s3.us-east-1.amazonaws.comReporting · reference↗weforum.orgReporting · reference↗youtube.comReporting · reference↗

Still resolving: Newsroom · Official X

Funding

Latest disclosed valuationNot disclosed
Tracked capital$76M2 sourced rounds

What it builds

H-Optimus-0

Bioptimus’s open-source foundation model for pathology, released with 1.1 billion parameters and trained on a proprietary dataset constructed from hundreds of millions of histopathology images extracted from more than 500,000 slides across thousands of clinical practices.

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H-Optimus-1

Bioptimus’s state-of-the-art histopathology foundation model; the company announced availability via AWS Marketplace for deployment in secure AWS environments and described tasks including cancer subtype classification, tumor grading, biomarker detection, and digital slide quality control.

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M-Optimus

Bioptimus’s “world model for biology,” positioned as a multi-modality model designed to simulate biology in its full complexity; the company described early access for pioneer clients and linked it to integrating multiple biological modalities (beyond pathology alone).

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STELA (Spatial Tissue Embedding Learning Atlas)

A multinational, clinically linked spatial data generation initiative described as the data engine intended to scale M-Optimus, aiming to profile up to 100,000 patient specimens and anchored by partnerships including 10x Genomics and Broad Clinical Labs.

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AWS Marketplace distribution for pathology models

Bioptimus announced that H-Optimus-1 is available on AWS Marketplace to allow healthcare and life sciences organizations to deploy its pathology model within their own secure cloud workflows.

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Key metrics

Milestones & partnerships

Aug 20, 2026
Cancer Research Horizons partnership adds UK cohort to STELA

Bioptimus announced access to S:CORT from Cancer Research Horizons and described it as the first UK cohort in STELA linked to its colorectal cancer coverage.

Cancer Research Horizons
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Jun 30, 2026
FFCD partnership expands STELA GI cancer data access

Bioptimus announced that FFCD partnership grants access to clinical trial data for more than 3,000 GI cancer patients and advances STELA’s dataset coverage.

Fédération Francophone de Cancérologie Digestive (FFCD)
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Mar 25, 2026
Launch of STELA (clinically linked spatial atlas)

Bioptimus announced STELA to profile up to 100,000 patient specimens and scale M-Optimus, anchored by partnerships including 10x Genomics and Broad Clinical Labs.

10x Genomics · Broad Clinical Labs
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Dec 17, 2025
Unveiling of M-Optimus

Bioptimus announced M-Optimus as its world model for biology with multi-modal capabilities and described an early access program for pioneer clients.

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Jun 11, 2025
NVIDIA DGX Cloud Lepton compute access

Bioptimus announced compute access through NVIDIA DGX Cloud Lepton to accelerate foundation model training.

NVIDIA · Sofinnova Partners
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May 06, 2025
H-Optimus-1 made available on AWS Marketplace

Bioptimus announced that H-Optimus-1 is available on AWS Marketplace for deployment in secure AWS environments.

Amazon Web Services (AWS)
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Jul 11, 2024
Release of H-Optimus-0 (open-source pathology foundation model)

Bioptimus announced H-Optimus-0 release, describing a 1.1B-parameter open-source pathology model trained on a proprietary multi-practice dataset.

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Feb 20, 2024
Out of stealth with $35M seed financing

Bioptimus announced its emergence from stealth and a $35M seed funding round to build a universal foundation model for biology across scales.

Sofinnova Partners · Bpifrance Large Venture
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