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Cradle

What Cradle does

Cradle is a private AI-for-science company building enterprise software for generative protein engineering. Its platform is designed for research teams in biopharma and industrial biology to generate and optimize protein candidates faster by iteratively learning from their own wet-lab experimental results, while keeping project data private to each organization. Cradle positions the workflow as “closed-loop” between computation and the lab, with plate/round-level optimization and guided execution to make multi-constraint protein engineering more consistent across iterations. The company also runs an internal wet lab used to validate and improve its models.

News

Company record

Aug 11, 2026 · Official · CradleOptimizing across the entire batch is one secret to better proteins

Cradle published a technical explainer of its plate-level design philosophy, describing probabilistic modeling, “error fingerprints,” and portfolio-style optimization for consistent experimental rounds.

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Jun 16, 2026 · Official · CradleIntroducing Guided Rounds

Cradle introduced “Guided Rounds,” describing best-practice workflow guidance inside the platform for setting up and running protein engineering rounds with defaults, process consistency, and traceable decision-making.

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Jun 09, 2026 · Official · CradleZero-shot antibody diversification with Cradle

Cradle described how it kicks off antibody diversification campaigns when scientists have limited or no campaign-specific assay training data, including claims about affinity improvements and success patterns.

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Jun 03, 2026 · Official · CradleLundbeck partners with Cradle to discover and optimize brain disorder treatments

Cradle announced a partnership with H. Lundbeck A/S to deploy Cradle’s AI-powered protein design platform for end-to-end AI-guided protein engineering workflows, with initial focus on two antibody programs targeting CNS diseases.

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Nov 26, 2024 · Official · CradleCradle raises $73M Series B to Put AI-Powered Protein Engineering in Every Lab

Cradle announced $73m in Series B led by IVP, with continued backing from Index Ventures and Kindred Capital, and outlined plans to expand wet lab capabilities and scale go-to-market/operations.

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Nov 28, 2023 · Official · CradleCradle raises $24M Series A and signs partnerships with industry leaders

Cradle announced a $24m Series A led by Index Ventures (with participation from Kindred Capital) and stated it had onboarded multiple industry partners and R&D projects focused on protein modalities and properties.

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Nov 17, 2022 · Official · CradleWe've raised $5.5M to design protein-machines and cell-factories with AI

Cradle announced exiting stealth and raising a seed round (€5.5m / $5.4m), co-led by Index Ventures and Kindred Capital, including named angel investors; the company also described its wet lab and generative ML approach to protein design.

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Still resolving: Newsroom · Official X

What it builds

Cradle protein engineering platform

An enterprise AI software platform that lets teams train and run generative protein AI using their own experimental data, with wet-lab validation and “round”/plate-level optimization to help generate candidates that meet multiple objectives faster than traditional workflows.

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Guided Rounds

A workflow capability inside Cradle intended to bring best-practice setup and process guidance for running a design/optimization “round” in a consistent, traceable way (while still allowing detailed configuration for advanced users).

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Cradle AI-assisted protein engineering for industrial teams

A solution page describing Cradle’s approach for industrial protein engineering teams, including the use of experimental data imports, simultaneous multi-objective optimization, and iterative learning across a program.

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Key metrics

Milestones & partnerships