← All companies & organizations

Science policy / Organization profile

University of Chicago Market Shaping Accelerator

What University of Chicago Market Shaping Accelerator does

The University of Chicago Market Shaping Accelerator (MSA) is an academic initiative focused on “market shaping” mechanisms—policy and incentive designs that make innovation financially viable when purely commercial incentives lag social value—applied to challenges such as pandemics and climate change. MSA’s core role is to translate market-shaping research and prior real-world examples (e.g., advance market commitments used in vaccine development) into proposals that governments, multilateral institutions, and philanthropies can adopt, typically by designing “pull” incentives (prizes, milestone contracts, and advance market commitments) rather than funding only upstream R&D. The organization is led by a small set of faculty directors from the University of Chicago and Dartmouth College, plus a director role held by Leah Rosenzweig at the Center for Global Development, and it runs an Innovation Challenge to identify, develop, and advance market-shaping proposals. Strategically, MSA positions itself as a connector between academic incentive design, domain expertise (health and climate), and funder/policymaker implementation pathways—aiming to help move from concept to contracts and (eventually) scaled deployment.

News

Company record

Aug 27, 2025 · Official · Market Shaping Accelerator at UChicagoHow “pull” funding can supercharge MAHA’s drug repurposing vision

MSA published a blog arguing for disease-agnostic pull funding approaches (rewarding outputs/outcomes) to overcome underinvestment in repurposed generic drug innovation, and discusses potential U.S. agencies/roles for structuring such incentives.

↗
Jun 23, 2025 · Official · Market Shaping Accelerator at UChicagoWhy Expertise Matters: Building the Coalition to Launch Our Neonatal Sepsis AMC

MSA describes a CGD–MSA working group convened to design an advance market commitment (AMC) for a rapid diagnostic test for neonatal sepsis in low- and middle-income countries, including the need for specialized health, economics, and policy expertise and the working group’s core activities.

↗
Jun 23, 2025 · Official · Market Shaping Accelerator at UChicagoWhen Markets Fail Newborns: The Case for an Advance Market Commitment for Neonatal Sepsis Diagnostics

MSA’s blog post (second in a series) makes the case for using an AMC to address under-incentivized diagnostics innovation for neonatal sepsis in low- and middle-income countries and explains the market failures and incentive design logic.

↗
Jun 23, 2025 · Official · Market Shaping Accelerator at UChicagoThe Case for Prioritizing Neonatal Sepsis Diagnostics

MSA’s blog post (first in a series) argues that neonatal sepsis diagnostics are a global priority and explains why diagnostic innovation can be held back by market failures and misaligned incentives.

↗
Jun 13, 2025 · Official · Market Shaping Accelerator at UChicagoDepartment of Health and Human Services: Don’t Put All Your Vaccine Shots in the Egg Basket

MSA published an analysis framing the U.S. Generation Gold Standard effort (universal flu/coronavirus vaccines) as a shift toward longer-lasting protection and argues for incentive/policy approaches that address limitations of strain-specific booster-vaccine paradigms.

↗
Oct 23, 2024 · Official · Market Shaping Accelerator at UChicagoFive steps multilateral development banks can take now to unlock pandemic financing

MSA and CGD collaborators discussed how multilateral development banks can enable at-risk financing for medical countermeasures for future pandemics, including convening a panel discussion on “Day Zero Dollars.”

↗
Sep 10, 2024 · Official · Market Shaping Accelerator at UChicagoAnnouncing winners of the inaugural MSA Innovation Challenge

MSA announced $600,000 in prizes for three proposals: broad-spectrum antivirals (to develop/stockpile), an AMC to accelerate neonatal sepsis diagnostics, and pull mechanisms for repurposing generic drugs.

↗
Sep 07, 2023 · Official · Market Shaping Accelerator at UChicagoUChicago’s Market Shaping Accelerator Awards 39 Innovation Prizes in the First Round of the $2M Competition

MSA reported that it awarded 39 innovation prizes in the first round of its $2 million Innovation Challenge and outlined how Phase I winners were advanced into Phase II for deeper pull-mechanism design.

↗
Show 2 earlier updates
Source map · 2 recurring channels · 52 references
University of Chicago Market Shaping AcceleratorOfficial Site · monitor↗MTS Frontier / Control RoomCurated Feed · monitor↗Official organization sourceOfficial Reference · reference↗80000hours.orgReporting · reference↗arxiv.orgReporting · reference↗bfi.uchicago.eduReporting · reference↗careeradvancement.uchicago.eduReporting · reference↗cgdev.orgReporting · reference↗chatgpt-windows.topReporting · reference↗cjche.github.ioReporting · reference↗de.wikipedia.orgReporting · reference↗dec.uchicago.eduReporting · reference↗digitalharbor.orgReporting · reference↗dil.uchicago.eduReporting · reference↗discovery.ucl.ac.ukReporting · reference↗en.wikipedia.orgReporting · reference↗eprints.lse.ac.ukReporting · reference↗faculty-directory.dartmouth.eduReporting · reference↗fas.dartmouth.eduReporting · reference↗founderspledge.comReporting · reference↗g2lm-lic.iza.orgReporting · reference↗gendagigo.jpReporting · reference↗griffincatalyst.orgReporting · reference↗idcrawl.comReporting · reference↗imf.orgReporting · reference↗innovationcaucus.co.ukReporting · reference↗innovationcommission.uchicago.eduReporting · reference↗jilbab.twstalker.comReporting · reference↗knowledge.uchicago.eduReporting · reference↗linkedin.comReporting · reference↗listennotes.comReporting · reference↗marketshapingaccelerator.orgReporting · reference↗microbiologysociety.orgReporting · reference↗mobile.twitter.comReporting · reference↗mobile.twstalker.comReporting · reference↗ngntipkolamrenang.twstalker.comReporting · reference↗prnewswire.comReporting · reference↗prometheusxtalent.comReporting · reference↗reddit.comReporting · reference↗schmidtfutures.comReporting · reference↗schmidtfutures.orgReporting · reference↗site.twstalker.comReporting · reference↗sloan.orgReporting · reference↗sotwe.comReporting · reference↗twitter.comReporting · reference↗twstalker.comReporting · reference↗uacj.mxReporting · reference↗urbanlabs.uchicago.eduReporting · reference↗usdigitalresponse.orgReporting · reference↗worksinprogress.coReporting · reference↗x.comReporting · reference↗x.comReporting · reference↗x.comReporting · reference↗x.comReporting · reference↗

Still resolving: Newsroom · Official X

Funding

Latest disclosed valuationNot disclosed
Tracked capital$8.8M7 sourced rounds
DateRoundRaisedValuationLead / investorsEvidence
Mar 01, 2025research_grant$966.4K—
Not attributed
+1 investor
Jan 01, 2025philanthropic_donation$155K—
Not attributed
+1 investor
Sep 10, 2024prize_awards$600K—
Not attributed
Sep 09, 2024Innovation Challenge awards (inaugural round)$600K—
May 25, 2023Innovation Challenge prize pot$2M—
May 04, 2023Program launch support (philanthropic)——
May 04, 2023Seed gift (Griffin Catalyst)$4.5M—

What it builds

MSA Innovation Challenge

An open-call-to-proposals program intended to surface and develop market-shaping proposals (focused on climate change and pandemic preparedness), using “pull” mechanisms such as prizes and advance market commitments, and advancing promising ideas toward contract-ready designs.

source ↗
Market Shaping Glossary (MSA glossary)

A public reference explaining commonly-used market-shaping terms used across MSA’s work (including the distinction between push and pull financing).

source ↗

Key metrics

Milestones & partnerships

Jun 23, 2025
Working group convened to design a neonatal sepsis AMC

MSA described a CGD–MSA working group convened to make the neonatal sepsis diagnostics AMC happen, including establishing target product profiles and specifying country participation and funding mobilization tasks.

Center for Global Development (CGD) · Lord Jim O’Neill
↗
Jun 13, 2025
Policy analysis on universal vaccine strategy and incentives

MSA published analysis about universal vaccine development efforts under HHS/NIH initiatives and why incentive design is important in the face of evolving virus strains.

U.S. Department of Health and Human Services · National Institutes of Health
↗
Oct 23, 2024
Collaboration on at-risk pandemic financing for LMICs

MSA and CGD collaborators highlighted barriers in pandemic vaccine delivery financing and discussed steps for multilateral development banks to unlock at-risk financing mechanisms.

Center for Global Development (CGD) · Gavi · U.S. International Development Finance Corporation · World Health Organization · World Bank Group
↗
Sep 09, 2024
Inaugural Innovation Challenge culminated with three awardees

MSA announced $600,000 in prizes for three market-shaping proposals (antivirals stockpile development; neonatal sepsis diagnostics AMC; and pull mechanisms for repurposed generic drugs).

Center for Global Development (CGD)
↗
Sep 07, 2023
Phase I prize round completed (39 winning teams)

MSA awarded 39 innovation prizes in the first round of its $2M competition and described the transition of Phase I winners into Phase II for detailed pull-mechanism design.

↗
May 25, 2023
Innovation Challenge prize program announced

MSA launched a $2 million Innovation Challenge to surface and develop pull-mechanism market shaping proposals for climate and pandemic/biosecurity priorities.

Schmidt Futures · Digital Harbor Foundation · Citadel (Ken Griffin)
↗
May 04, 2023
MSA launched as an initiative to accelerate market-shaping approaches

UChicago announced the launch of the Market Shaping Accelerator focused on climate change, biosecurity, and pandemic preparedness using market-shaping incentives (e.g., advance market commitments, prizes, and milestone contracts).

Schmidt Futures · Citadel (Ken Griffin) · Digital Harbor Foundation
↗