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SandboxAQ

What SandboxAQ does

SandboxAQ is an enterprise AI company that positions itself at the intersection of AI and quantum techniques, using what it calls Large Quantitative Models (LQMs) to generate physics/chemistry-grounded results for real-world use cases. The company’s go-to-market centers on B2B deployments and integrations of domain models into existing enterprise workflows, with distribution increasingly connected to common AI interfaces (notably Claude via Model Context Protocol) and cloud marketplaces. Its product surface includes quantitative models for catalysis/materials discovery (AQCat/AQChemSim), drug discovery and potency prediction (AQPotency/AQBioSim, plus AQAffinity as an open binding-affinity model), cybersecurity and cryptographic agility tooling (AQtive Guard), and GPS-denied navigation (AQNav). SandboxAQ also reports moving deeper into agentic/enterprise AI operations with “Switch” (open-sourced) and expanding into national-security and industrial manufacturing work via large CHIPS R&D funding for semiconductor-related formulations. The strategic picture from recent public releases suggests SandboxAQ is working to industrialize and distribute its LQM capabilities broadly (Claude, AWS Marketplace, Google Cloud Marketplace) while targeting regulated, high-stakes buyers in defense, healthcare/life sciences, chemicals/materials, and critical infrastructure.

News

Company record

Sep 09, 2026 · Official · SandboxAQSandboxAQ Completes Successful Flight Test of AQNav’s Quantum Navigation Technology on Northrop Grumman’s Lumberjack® Attritable Unmanned Aircraft System (UAS)

SandboxAQ reported a flight test of its AQNav magnetic-navigation technology integrated with Northrop Grumman’s Lumberjack attritable UAS, positioning AQNav as continuous, GPS-denied navigation that can integrate as software into existing navigation stacks.

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Aug 26, 2026 · Official · SandboxAQSandboxAQ Open Sources Switch: Bring Any AI Agent Into Any Team Chat

SandboxAQ announced Switch, described as open-source software that enables shared rooms in Slack, Microsoft Teams, Discord and other collaboration tools so human teams and AI agents can collaborate with preserved context and history.

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Aug 25, 2026 · Official · SandboxAQSandboxAQ Accelerates Fortune 500 Catalyst Discovery with AQCat, Now Generally Available in AWS Marketplace

SandboxAQ announced AQCat is generally available in AWS Marketplace and deployable through Amazon SageMaker, describing a shift from bespoke engagements to self-service distribution inside customer AWS environments.

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Aug 19, 2026 · Official · SandboxAQSandboxAQ Makes AQCat Generally Available on Claude for High-Throughput Catalyst Screening

SandboxAQ announced AQCat is generally available on Claude Science via Model Context Protocol (MCP), enabling catalyst screening through natural-language prompts without coding.

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Aug 19, 2026 · Official · SandboxAQSandboxAQ Launches AQPotency, Bringing Ultrafast Virtual Screening to Drug Discovery Without a Solved Protein Structure

SandboxAQ announced general availability of AQPotency on Claude via MCP, describing it as structure-free virtual screening/potency scoring that also reports confidence and whether targets fall within the model’s reliable range.

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Jun 29, 2026 · Official · SandboxAQSandboxAQ to Bring Large Quantitative Models to Google Cloud's Marketplace

SandboxAQ announced its plan to make LQMs available through Google Cloud’s Marketplace, with AQCat first (and AQPotency following) and positioned for access via conversational AI tools without specialized code or infrastructure.

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Jun 23, 2026 · Official · SandboxAQSandboxAQ Launches Virtual Screening Solution for GPCR Drug Discovery, Accelerated by NVIDIA BioNeMo

SandboxAQ announced a GPCR virtual screening solution accelerated by NVIDIA BioNeMo Agent Toolkit, positioning it as a physics-based approach that predicts both binding and whether molecules act as agonists/antagonists/inverse agonists across receptor conformations.

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Jun 22, 2026 · Official · SandboxAQSandboxAQ Supports White House Executive Order as Post-Quantum Cryptography Moves to Implementation for National Security

SandboxAQ issued a statement around White House Executive Order 14409 on post-quantum cryptography, describing federal migration milestones and stating the company will partner with federal agencies to modernize cryptography at scale.

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Show 4 earlier updates
Jun 17, 2026 · Official · SandboxAQSandboxAQ Signs Definitive Agreement with the US Department of Commerce for $500 Million CHIPS R&D Award

SandboxAQ announced a $500 million CHIPS R&D award to develop and commercialize semiconductor-manufacturing critical formulations, with work spanning PFAS-free chemicals, catalysts, rare-earth-free magnets, and battery systems; Commerce will receive a minority, non-voting equity stake.

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May 18, 2026 · Official · SandboxAQSandboxAQ Integrates its Quantitative AI Models with Anthropic's Claude via MCP

SandboxAQ announced integration of its Large Quantitative Models with Anthropic’s Claude via MCP, describing a shift from requiring specialized code/infrastructure to using natural-language prompts for access to quantitative models.

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Jan 20, 2026 · Official · SandboxAQSandboxAQ Supercharges OpenFold3 with AQAffinity: High-Speed, Structure-Free Drug Potency Prediction

SandboxAQ announced launch of AQAffinity built on OpenFold3 co-folding, positioned as a structure-free binding affinity/potency prediction model to unblock early-stage drug discovery bottlenecks.

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Dec 18, 2024 · Official · SandboxAQSandboxAQ Announces More Than $300 Million of Funding to Drive Next Era of AI

SandboxAQ announced a round of more than $300 million and stated the round valued the company at $5.3B pre-money; it described acceleration of LQMs and AI solutions across drug discovery, materials science/chemistry, cybersecurity, navigation, and medical devices.

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Source map · 3 recurring channels · 59 references
SandboxAQOfficial Site · monitor↗Eric Schmidt on XPrincipal X · monitor↗MTS Frontier / Control RoomCurated Feed · monitor↗go.sandboxaq.comOfficial Reference · reference↗Official company sourceOfficial Reference · reference↗sec.govRegulatory · reference↗aibmag.comReporting · reference↗algos.quantumleap.blogReporting · reference↗app.dealroom.coReporting · reference↗app.uselegion.comReporting · reference↗applyguy.aiReporting · reference↗assets-us-01.kc-usercontent.comReporting · reference↗axios.comReporting · reference↗beyondalphaventures.comReporting · reference↗bizjournals.comReporting · reference↗boards.greenhouse.ioReporting · reference↗caplight.comReporting · reference↗capstonepartners.comReporting · reference↗cbinsights.comReporting · reference↗cio.comReporting · reference↗clay.comReporting · reference↗crunchbase.comReporting · reference↗defillama.comReporting · reference↗en.wikipedia.orgReporting · reference↗fii-institute.orgReporting · reference↗forbes.comReporting · reference↗forgeglobal.comReporting · reference↗groowe.comReporting · reference↗hpcwire.comReporting · reference↗intro-act.comReporting · reference↗investing.comReporting · reference↗ir.datavaultsite.comReporting · reference↗itpro.comReporting · reference↗linkedin.comReporting · reference↗markets.ft.markitdigital.comReporting · reference↗morningstar.comReporting · reference↗nist.govReporting · reference↗owler.comReporting · reference↗paladincapgroup.comReporting · reference↗parkway.vcReporting · reference↗pdf.secdatabase.comReporting · reference↗pr.bluemountaineagle.comReporting · reference↗prnewswire.comReporting · reference↗public.comReporting · reference↗qatlas.coReporting · reference↗quantumleap.blogReporting · reference↗reddit.comReporting · reference↗rothschildandco.comReporting · reference↗s201.q4cdn.comReporting · reference↗s21.q4cdn.comReporting · reference↗sandiego.govReporting · reference↗sdrventures.comReporting · reference↗seedtable.comReporting · reference↗siliconvalleyinvestclub.comReporting · reference↗startupfundraising.comReporting · reference↗stockanalysis.comReporting · reference↗storage.mfn.seReporting · reference↗sunriseranch.orgReporting · reference↗techcrunch.comReporting · reference↗thequantuminsider.comReporting · reference↗weforum.orgReporting · reference↗wsj.comReporting · reference↗

Still resolving: Newsroom · Official X

Funding

Latest disclosed valuation$13.9B
Tracked capital$1.8B5 sourced rounds
DateRoundRaisedValuationLead / investorsEvidence
Jun 17, 2026CHIPS Research & Development Office award (U.S. government R&D agreement)$500M—
May 21, 2026Series F (disclosed amount/valuation reported; investors not disclosed in source)$500M$13.9B
Not attributed
Mar 22, 2022Launch funding round (post–Alphabet spinout; amount not disclosed)——

What it builds

AQCat

AQCat is SandboxAQ’s Large Quantitative Model for catalyst discovery, designed to accelerate adsorption-energy calculations for high-throughput catalyst screening and candidate ranking.

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AQPotency

AQPotency is SandboxAQ’s LQM for drug discovery that predicts protein-ligand potency (pIC50) without requiring experimentally resolved 3D structures, with confidence-aware scoring and off-target screening.

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AQAffinity

AQAffinity is an open-source binding-affinity prediction model built on the OpenFold3 ecosystem, enabling structure-free potency prediction from sequences to support early-stage virtual screening workflows.

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AQNav

AQNav is SandboxAQ’s software-first MagNav navigation solution intended to provide assured positional intelligence in GPS-denied environments, including sensor-agnostic, open-architecture integration into existing navigation stacks.

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AQtive Guard

AQtive Guard is SandboxAQ’s enterprise security and cryptographic management software suite, positioned to inventory and assess AI and cryptography risks and enable enforcement/remediation (including crypto-agility and PQC migration support).

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Switch

Switch is open-sourced software for bringing AI agents into enterprise collaboration tools (e.g., Slack and Microsoft Teams) by creating shared rooms/channels so human and agent work can share the same context and history.

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Key metrics

Milestones & partnerships

Sep 09, 2026
AQNav flight test on Northrop Grumman Lumberjack UAS

SandboxAQ reported completion of a flight test of AQNav magnetic navigation integrated with Northrop Grumman’s attritable Lumberjack UAS.

Northrop Grumman
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Aug 25, 2026
AQCat generally available via AWS Marketplace / SageMaker

SandboxAQ announced AQCat was generally available in AWS Marketplace and deployable through Amazon SageMaker for self-service catalyst discovery workflows.

Amazon (AWS)
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Jun 17, 2026
CHIPS R&D definitive agreement for $500M award

SandboxAQ reported a $500 million CHIPS R&D award from the U.S. Department of Commerce, including stated workstreams for semiconductor-related chemicals, catalysts, magnets, and battery systems and a minority, non-voting equity stake for Commerce.

U.S. Department of Commerce
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May 18, 2026
Claude/MCP integration for LQM access

SandboxAQ announced integration of its LQMs with Anthropic’s Claude via MCP to connect natural-language interfaces to quantitative model capabilities.

Anthropic
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Apr 04, 2025
Closed Series E (over $450M) and expanded investor base

SandboxAQ announced the closing of a Series E round raising over $450 million and the addition of new investors including Ray Dalio, Horizon Kinetics, BNP Paribas, Google, and NVIDIA.

Ray Dalio · BNP Paribas · Google · NVIDIA
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Dec 18, 2024
Stated $5.3B pre-money valuation in a $300M+ funding announcement

SandboxAQ publicly stated the valuation and investor list for a round described as more than $300 million to accelerate LQMs and AI applications.

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Mar 22, 2022
Independent launch and initial customer/investor/board disclosure

SandboxAQ launched as an independent venture-backed entity and described early customers, board leadership, and an oversubscribed funding round at launch.

Vodafone Business · Mt. Sinai Health System · Wix · Softbank Mobile
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